Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production
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چکیده
منابع مشابه
Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production.
Discoidin domain receptor (DDR)1 is an extracellular matrix (ECM)-sensing receptor tyrosine kinase, which is activated by collagen and expressed in bronchial epithelium. DDR1 is responsible for maintaining the normal structure of skin and kidney epithelia and we hypothesised that DDR1 plays a regulatory role in bronchial epithelial integrity by transducing signals from the airway ECM. Effects o...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2010
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00039710